|
KMID : 0604520110370030247
|
|
Journal of the Society of Cosmetic Scientists of Korea
2011 Volume.37 No. 3 p.247 ~ p.256
|
|
|
Embryo-Fetal Developmental Toxicity Study of Methoxycinnamidopropyl Polysilsesquioxane
|
|
Hong Jeong-Sup
Lim Jeong-Hyeon
Kim Kang-Hyun
Park Myeong-Kyu
Jo Ki-Yeon
Park Gil-Jong
Jung Taek-Kyu
Kim Ja-Young
Yoon Kyung-Sup
|
|
|
Abstract
|
|
|
|
Existing organic UV protection materials seem to be problematic due to their penetration and irritation to skin. Inorganic UV protection materials are also at issue for safety of their nano-type transformation. Therefore, the recent studies of UV protection materials have been focused not only on the effectiveness but also on their safety. One of the UV protection materials in study which have higher safety is the organic-inorganic conjugation type UV protection material. Previously, we have reported the manufacturing process, physical property and UV protection efficiency of methoxychinnamidoprophy poloysilsesquixan as a new cross-linked polymer type UV protection material. In this study, we have evaluated the effect of the methoxychinnamidoprophy poloysilsesquixan on embryo-fetal de-velopment in SD rats. This study is expected to show some definite information related to the effect on pregnancy or embryo-fetal abnormality in case of the clinical exposure of the methoxychinnamidoprophy poloysilsesquixan.
|
|
|
KEYWORD
|
|
|
reproductive developmental toxicity, embryo-fetal developmental toxicity, UV screening agent, methoxycinnamidopropyl polysilsesquioxane
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|